Allergan and ACADIA Pharmaceuticals Announce New Drug Discovery and Development Collaboration
Collaboration to Pursue Numerous Target-Specific Chemistries in Eye Care
and Other Indications
SAN DIEGO, CA, April 15, 2003 - ACADIA Pharmaceuticals announced today
it has established a new drug discovery and development collaboration with Allergan,
Inc. (NYSE: AGN). The collaboration, which will focus predominantly on eye care
applications, combines ACADIA's chemical-genomics platform and discovery assets
with Allergan's world-class expertise in the discovery, development and commercialization
of innovative new therapeutics. This new agreement represents the parties' third
major collaboration since 1997.
The collaboration will leverage ACADIA's extensive base of biological and chemical
assets, including novel chemistries that ACADIA has identified for a wide range
of G-protein coupled receptor and nuclear receptor targets. Under the agreement,
the parties will use these target-specific chemistries to explore a range of
discovery opportunities. Allergan will have the exclusive right to license chemistry
and related assets for up to three drug targets. ACADIA will receive an upfront
payment, research funding and additional fees over a three-year term. ACADIA
is also eligible to receive license fees and milestone payments as well as royalties
on future product sales worldwide. Assuming the successful development of a
product for just one of the drug targets, ACADIA will receive up to $32 million
in aggregate payments, excluding royalties.
"This collaboration provides Allergan with an opportunity to explore potential
drug targets and novel chemistries for eye care and other strategic applications,"
said Lester J. Kaplan, Ph.D., Allergan's President of R&D. "We look
forward to the discovery of new therapeutic approaches for a range of important
"We are delighted to expand our strong scientific collaboration with Allergan,"
said Mark R. Brann, Ph.D., President and CSO of ACADIA. "Our teams work
very well together, and the science of this new collaboration is going to be
especially exciting. With so many target-specific chemistries, we have an unprecedented
number of approaches to explore. Combining this with Allergan's exceptional
strength in eye care research, we hope to identify completely new approaches
to the treatment of various ophthalmic diseases."
ACADIA Pharmaceuticals is a drug discovery and development company that efficiently
discovers novel small molecule drug candidates using its proprietary chemical-genomics
platform. ACADIA has applied its platform to generate a broad discovery pipeline
directed at large unmet medical needs including Parkinson's disease, chronic
pain, psychosis, and glaucoma. Two of ACADIA's drug candidates have been successfully
advanced from initial discovery to clinical development, and several additional
programs are in late-stage preclinical testing. ACADIA's corporate headquarters
as well as its biological research facilities are located in San Diego, California
and its chemistry research facilities are located in Copenhagen, Denmark.
Allergan, Inc., with headquarters in Irvine, California, is a technology-driven, global health care company providing eye care and specialty pharmaceutical products worldwide. Allergan develops and commercializes products in the eye care, neuromodulator and skin care markets that deliver value to our customers, satisfy unmet medical needs, and improve patients' lives.
Mark R. Brann, Ph.D., President and CSO
Douglas E. Richards, VP of Business Development
+1 858 558 2871